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Jackson takes the roster spot that opened when right-hander Paul Byrd was traded to the Boston Red Sox on Tuesday.
"I'm very excited," said Jackson, who is scheduled to start Thursday night against the Baltimore Orioles. "It is unusual to get an opportunity with a new team in the middle of a season.
"I was shocked by the trade, but it is an honor to be in a deal with such a big-name player. It's good to be wanted."
The 25-year-old Jackson went 3-1 with a 4.05 ERA in four starts and four relief appearances at Buffalo.
Jackson made his major league debut with the Brewers on June 4, 2006, and went 2-2 with a 5.40 ERA over seven starts and one relief appearance for Milwaukee that season. He spent the 2007 season at Triple-A Nashville, going 11-10 with a 4.46 ERA in 28 starts.
He made two relief appearances this season for Milwaukee, compiling a 4.91 ERA and no record.
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